I always like to start from the beginning. I feel like in this group, there's some of the most OG scientists, academics that have really set the field for our modern understanding of metabolic health and ketosis. Latt Mansor, and of course our esteemed guests, doctors Angela Poff and Dom D'Agostino. We've been on a super long hiatus, so I can't think of a better opportunity to re-jumpstart the podcast. Hey everyone, this is Geoffrey Woo on the HVMN Podcast. What is the best level of blood ketones to reach in order to get all the optimal benefit in performance as well as therapeutic targets? Is it higher the better, or is there a Goldilock's zone? Are you curious to find out? Well, tune in and let's get right into it. On top of that, most importantly, we also covered a question that most of you guys ask all the time. In this episode, we covered everything around ketone research, including cardiovascular disease, cancers, psychiatry, neurodegenerative diseases, athletic performance, or even space exploration, so stay tuned. Angela Poff, talking about the current state of ketone research in 2022. Now, I know we have taken quite a long hiatus, but what a better way to relaunch HVMN podcast with this episode where my co-host, Geoff Woo, and myself interviewed Dr. Latt Mansor, Research Lead of Health via modern nutrition here on HVMN Podcast. plant-based diets Watch Now Listen Now Transcription Optimal blood ketone levels for health benefits.Mitochondrial protection in astronauts in space.Athletic performance/ extreme environment.Key point topics and studies mentioned: Role of ketones and the future direction of ketone research in: Poff in person to talk about the state of the art of ketone research in 2022. Angela Poff is a Research Associate in the Department of Molecular Pharmacology and Physiology at the University of South Florida in Tampa, FL, and Co-Founder of Metabolic Health Initiative. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC). Dominic D’Agostino is an Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine.
His research is supported by the Office of Naval Research (ONR), Department of Defense (DoD), private organizations and foundations.Dr. He was a research investigator and crew member on NASA’s Extreme Environment Mission Operation (NEEMO 22) and has a personal interest in environmental medicine and methods to enhance safety and physiological resilience in extreme environments. The main focus of his lab over the last 12 years has investigating the anticonvulsant and neuroprotective mechanism of the ketogenic diet and ketone metabolite supplementation. This approach can be used to treat a wide variety of pathologies linked pathophysiologically to metabolic dysregulation. Other areas of interest include researching metabolic-based drugs for cancer. His laboratory develops and tests metabolic-based strategies for targeting CNS oxygen toxicity (seizures), epilepsy, neurodegenerative diseases, brain cancer and metastatic cancer. He runs the website Keto Nutrition, and has been on over 200 podcasts talking about metabolic health. Dominic D’Agostino is a tenured Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine.
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